Table 1 Demographic characteristics, clinical characteristics and outcomes of 58 patients with palatal adenoid cystic carcinoma
Parameter | No. Of cases (%) | Survival without disease (%) | Survival with recurrence (%) | Death (%) | P-value |
|---|---|---|---|---|---|
Sex | 0.683 | ||||
Male | 28 (48.3) | 19/28 (67.9) | 4/28 (14.2) | 5/28 (17.9) | |
Female | 30 (51.7) | 22/30 (73.3) | 5/30 (16.7) | 3/30 (10.0) | |
Age (y) | 0.665 | ||||
≤ 60 years | 47 (81.0) | 32/47 (68.1) | 8/47 (17.0) | 7/47 (14.9) | |
> 60 years | 11 (19.0) | 9/11 (81.8) | 1/11 (9.1) | 1/11 (9.1) | |
Tumor size (cm) | 0.109 | ||||
≤ 2 cm | 9 (15.5) | 9/9 (100.0) | 0/9 (00.0) | 0/9 (0.0) | |
> 2 cm | 49 (84.5) | 32/49 (65.3) | 9/49 (18.4) | 8/49 (16.3) | |
Histopathologic grade | 0.0001 | ||||
Low grade (I + II) | (14 + 18) (55.2) | 30/32 (90.6) | 0/32 (0.00) | 2/32 (6.3) | |
High grade (III + transformed) | (23 + 3) (44.8) | 11/26 (42.3) | 9/26 (34.6) | 6/26 (23.1) | |
Perineural invasion | 0.281 | ||||
Absent | 10 (17.2) | 9/10 (90.0) | 1/10 (10.0) | 0/10 (0.0) | |
Present | 48 (82.8) | 32/48 (66.6) | 8/48 (16.7) | 8/48 (16.7) | |
Bone invasion | 0.250 | ||||
Absent | 6 (10.3) | 6/6 (100.0) | 0/6 (00.0) | 0/6 (100.0) | |
Present | 52 (89.7) | 35/52 (67.3) | 9/52 (17.3) | 8/52 (15.4) | |
Lymph node metastasis | 0.015 | ||||
Absent | 55 (94.8) | 41/55 (74.6) | 7/55 (12.7) | 7/55 (12.7) | |
Present | 3 (5.2) | 0/3 (0.0) | 2/3 (66.7) | 1/3 (33.3) | |
TNM stage | 0.0001 | ||||
Early (I + II) | (9 + 35) (75.9) | 39/44 (88.7) | 2/44 (4.5) | 3 /44 (6.8) | |
Advanced (III + IV) | (11 + 3) (24.1) | 2/14 (14.3) | 7/14 (50.0) | 5/14 (35.7) | |
Treatment | 0.004 | ||||
Radical excision | 44 (75.9) | 36/44 (81.8) | 4/44 (9.1) | 4/44 (9.1) | |
Radical excision with radiotherapy | 14 (24.1) | 5/14 (35.7) | 5/14 (35.7) | 4/14 (28.6) | |
Surgical margin | 0.081 | ||||
R0 | 56 (96.6) | 41/56 (73.2) | 8/56 | 7/56 | |
R1 | 2 (3.4) | 0/2 (0.0) | (14.3) 1/2 (50.0) | (12.5) 1/2 (50.0) | |
Ki-67 expressiona | 0.003 | ||||
Low | 40 (76.9) | 31/40 (77.5) | 5/40 (12.5) | 4/40 (10.0) | |
High | 12 (23.1) | 3/12 (25.0) | 4/12 (33.3) | 5/12 (41.7) |