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Table 3 Association between common variants and cephalometric parameter

From: Targeted sequencing of NOTCH signaling pathway genes and association analysis of variants correlated with mandibular prognathism

SNP-Gene-Function A1/A2 Phenotype parameters BETA SE P
rs1051415-JAG1-exon C/T Anterior-posterior facial height ratio (%) 2.50 0.86 0.0041
rs2272591-JAG2-exon A/G Mandibular body length (mm) −2.12 0.81 0.0093
rs10149229-JAG2-exon A/G Mandibular body length (mm) −2.80 0.82 0.00074
rs1057744-JAG2-exon C/T Facial angle (°) 34.08 15.41 0.028
y axis (°) 1.06 0.45 0.020
rs386591752-NOTCH4-exon T/C ANB angle (°) −1.58 0.48 0.0012
Wits appraisal (mm) −2.42 0.72 0.0010
APDI index(°) 1.79 0.64 0.0054
Facial convexity(°) −3.65 1.10 0.0011
Overjet (mm) −1.69 0.53 0.0017
rs372504208-NOTCH2-exon CGG/C Articularangle (S-Ar-Go) (°) −1.89 0.83 0.025
rs1044009-NOTCH3- exon G/A APDI index(°) −1.25 0.54 0.022
rs2304223-DLL3-intron C/G ANB angle (°) −0.73 0.34 0.033
Facial angle (°) −51.70 24.83 0.039
rs20551-EP300-exon A/G Midface length (mm) −2.91 1.44 0.045