Skip to main content

Advertisement

Table 1 Frequency of histologic types of head and neck lymphoma including also epidemiology, symptomatology, disease manifestations, localization and laboratory findings

From: Clinical presentation and characteristics of lymphoma in the head and neck region

  Indolent lymphoma Aggressive lymphoma Highly aggressive lymphoma Hodgkin lymphoma p-value
n 77 110 6 28  
Age      < 0.0001
 Mean ± SD 72 ± 39 66 ± 16 41 ± 24 41 ± 21  
 Median 70 70 34 33  
Gender, n [%]      0.11
 Male 37 [48] 57 [52] 6 [100] 14 [50]  
 Female 40 [52] 53 [48] 0 14 [50]  
First Diagnosis, n [%] 62 [81] 90 [82] 5 [83] 27 [96] 0.26
Time to diagnosis, [Months]      0.22
 Mean ± SD 7.5 ± 11.5 3.7 ± 8.5 1.5 ± 0.7 3.4 ± 3.5  
 Median 3.0 2.0 1.5 1.5  
Leading symptom      0.045
 Cervical mass 62 [81] 76 [69] 3 [100] 27 [96]  
 Globus pharyngis 3 [4] 6 [5] 0 0  
 Odyno−/dysphagia 7 [9] 21 [19] 3 [100] 1 [4]  
 Dysphonia 0 1 [1] 0 0  
 Dyspnea 2 [3] 3 [3] 0 0  
 Incidentally 2 [3] 3 [3] 0 0  
Localization, n [%]      < 0.0001
 Major salivary gland 21 [27] 12 [11] 0 0  
 Sinonasal system 2 [3] 4 [4] 0 0  
 Tonsils 15 [20] 41 [37] 3 [50] 1 [4]  
 Hypopharynx/Larynx 1 [1] 6 [6] 0 0  
 Lymph node 37 [48] 43 [39] 3 [50] 27 [96]  
 Other 1 [1] 4 [4] 0 0  
Laterality, n [%]      0.62
 Unilateral 65 [85] 90 [82] 6 [100] 22 [79]  
 Bilateral 12 [15] 20 [18] 0 6 [21]  
Systemic disease, n [%] 43 [56] 75 [68] 6 [100] 22 [79] 0.90
B-symptoms, n [%] 5 [7] 20 [18] 0 3 [11] 0.30
Laboratory parameter, Mean ± SD
 Leucocytes 11.8 ± 12.0 7.7 ± 3.6 4.5 ± 3.2 8.0 ± 3.0 0.043
 Hemoglobin 13.6 ± 1.9 13.4 ± 2.3 10.4 ± 6.1 13.0 ± 2.9 0.24
 CRP 1.53 ± 2.88 1.80 ± 3.00 1.20 ± 2.00 3.30 ± 4.30 0.15
 LDH 263 ± 285 278 ± 291 232 ± 229 271 ± 121 0.97
  1. aNHL Aggressive non-Hodgkin lymphoma, haNHL Highly aggressive non-Hodgkin lymphoma, HL Hodgkin lymphoma, iNHL Indolent non-Hodgkin lymphoma