Table 1 Frequency of histologic types of head and neck lymphoma including also epidemiology, symptomatology, disease manifestations, localization and laboratory findings

n

77

110

6

28

Age

< 0.0001

 Mean ± SD

72 ± 39

66 ± 16

41 ± 24

41 ± 21

 Median

70

70

34

33

Gender, n [%]

0.11

 Male

37 [48]

57 [52]

6 [100]

14 [50]

 Female

40 [52]

53 [48]

0

14 [50]

First Diagnosis, n [%]

62 [81]

90 [82]

5 [83]

27 [96]

0.26

Time to diagnosis, [Months]

0.22

 Mean ± SD

7.5 ± 11.5

3.7 ± 8.5

1.5 ± 0.7

3.4 ± 3.5

 Median

3.0

2.0

1.5

1.5

Leading symptom

0.045

 Cervical mass

62 [81]

76 [69]

3 [100]

27 [96]

 Globus pharyngis

3 [4]

6 [5]

0

0

 Odyno−/dysphagia

7 [9]

21 [19]

3 [100]

1 [4]

 Dysphonia

0

1 [1]

0

0

 Dyspnea

2 [3]

3 [3]

0

0

 Incidentally

2 [3]

3 [3]

0

0

Localization, n [%]

< 0.0001

 Major salivary gland

21 [27]

12 [11]

0

0

 Sinonasal system

2 [3]

4 [4]

0

0

 Tonsils

15 [20]

41 [37]

3 [50]

1 [4]

 Hypopharynx/Larynx

1 [1]

6 [6]

0

0

 Lymph node

37 [48]

43 [39]

3 [50]

27 [96]

 Other

1 [1]

4 [4]

0

0

Laterality, n [%]

0.62

 Unilateral

65 [85]

90 [82]

6 [100]

22 [79]

 Bilateral

12 [15]

20 [18]

0

6 [21]

Systemic disease, n [%]

43 [56]

75 [68]

6 [100]

22 [79]

0.90

B-symptoms, n [%]

5 [7]

20 [18]

0

3 [11]

0.30

 Leucocytes

11.8 ± 12.0

7.7 ± 3.6

4.5 ± 3.2

8.0 ± 3.0

0.043

 Hemoglobin

13.6 ± 1.9

13.4 ± 2.3

10.4 ± 6.1

13.0 ± 2.9

0.24

 CRP

1.53 ± 2.88

1.80 ± 3.00

1.20 ± 2.00

3.30 ± 4.30

0.15

 LDH

263 ± 285

278 ± 291

232 ± 229

271 ± 121

0.97