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Table 1 Distribution of bone tissue observed inside experimental cranial epidural space identified by BS-SEM [17, 18]

From: Novel use of cranial epidural space in rabbits as an animal model to investigate bone volume augmentation potential of different bone graft substitutes

Tissue Sample with β-TCP Sample with BCP
Bone tissue/Total observed area × 100 63.6% +/− 8.7 * 48.5% +/− 9.4
Vascular and Medullary cavity/Total observed area × 100 29.5% +/− 8.4 38.2% +/− 7.2
Characteristics of bone tissue Chondroid/tissue Total bone area × 100 5.1% +/− 2.2 3.1% +/− 3
Woven bone/Total bone area × 100 19.3% +/− 6.2 16.4% +/− 8.1
Lamellar bone/Total bone area × 100 78.4% +/− 9.5 85.7% +/− 13.3
  1. Percentage distribution of tissues observed in the experimental samples by BS-SEM. The “total observed area” involves all of tissue observed in the epidural space including biomaterial particles, in a frontal cut of sample (as showed in Fig. 2). The “total bone area” involves only the bone tissue (without biomaterial particles) observed in a frontal cut of samples. BCP samples reveal a more mature profile of osseous tissue than β-TCP with higher amounts of lamellar bone, albeit the difference is not significant
  2. *Significant difference (p<0,05)