Figure 5

Figure 5A: Evaluation of PCNA immunostaining at 1, 3 and 7 days after implantation of beads alone or beads loaded with A+4 or A-4. RP59 (osteogenic differentiation) (5B) and osteopontin (OPN) (5C) immunolabeling for beads alone (B), beads loaded with A+4 and A-4, at 1, 3 and 7 days after implantation. No staining is scored 0; ± = 0.5; + = 1; between + and ++, depending on sections = 1.5; and ++ = 2.