Figure 3From: Recent technological developments: in situ histopathological interrogation of surgical tissues and resection marginsInitial microendoscopic examination (x60) of buccal mucosa stained with methylene blue showing an area of high nuclear density visible as a streak. This is because at the microscopic level the epithelial surfaces are ruffled or concertinaed which distorts the image viewed and causes the impression of a high nuclear density per image field.Back to article page