Table 3 Primary and secondary risk factors for OSCC after exact matching of cases and controls
From: The role of family history of Cancer in Oral Cavity Cancer
Primary factors | Cases n = 255 n (%) | Controls n = 255 n (%) | p-value | Odds ratio (95% CI) |
|---|---|---|---|---|
Prior personal cancer history | 24 (9.4) | 31 (12.1) | 0.25 | |
Solid cancer (excluding HNC) | 16 (6.3) | 29 (11.4) | 0.05 | 0.53 (0.28–1.0) |
Hematologic cancer | 1 (0.4) | 2 (1.2) | 0.21 | 0.5 (0.04–5.5) |
Prior HNC | 7 (3.5) | 0 (0.0) | 0.99 | N/A |
Secondary factors | ||||
History of dysplasia/leukoplakia | 47 (18.4) | 3 (1.2) | < 0.01 | 15.6 (4.87–50.3) |
History of head and neck RT | 7 (2.7) | 0 (0.0) | 0.99 | N/A |