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Table 3 Primary and secondary risk factors for OSCC after exact matching of cases and controls

From: The role of family history of Cancer in Oral Cavity Cancer

Primary factors Cases
n = 255
n (%)
Controls
n = 255
n (%)
p-value Odds ratio (95% CI)
Prior personal cancer history 24 (9.4) 31 (12.1) 0.25  
 Solid cancer (excluding HNC) 16 (6.3) 29 (11.4) 0.05 0.53 (0.28–1.0)
  Hematologic cancer 1 (0.4) 2 (1.2) 0.21 0.5 (0.04–5.5)
  Prior HNC 7 (3.5) 0 (0.0) 0.99 N/A
Secondary factors
 History of dysplasia/leukoplakia 47 (18.4) 3 (1.2) < 0.01 15.6 (4.87–50.3)
 History of head and neck RT 7 (2.7) 0 (0.0) 0.99 N/A
  1. HNC Head and neck cancer. RT Radiation therapy