Fig. 4

Transcriptional regulation of IBA-1 in PDL cells upon CII and endocannabinoid treatment. Gene expression analyses for IBA-1 were performed upon challenge with or without AEA (50 μM) or PEA (50 μM) under serum-free conditions in combination with or without CII of PDL cells for 6 h or 10 h, respectively. Analyses were performed via qRT-PCR. Values represent the mean ± SEM (n = 6) of the relative differential gene expression (fold of control). The level for statistical significance was set at p < 0.05 (* p < 0.05, ** p < 0.01, *** p < 0.001)