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Fig. 2 | Head & Face Medicine

Fig. 2

From: Analogous modulation of inflammatory responses by the endocannabinoid system in periodontal ligament cells and microglia

Fig. 2

Transcriptional regulation of inflammatory cytokines and CB receptors in microglia upon CII and endocannabinoid treatment. Gene expression analyses were performed for IL-1ß (a), TNFa (b), IL-6 (c), CB1 (d) and CB2 (e) upon challenge with or without AEA (50 μM) or PEA (50 μM) under serum-free conditions in combination with or without CII of Embryonic stem cell-derived microglia (ESdM) cells for 6 h or 10 h, respectively. Analyses were performed via qRT-PCR. Values represent the mean ± SEM (n = 6) of the relative differential gene expression (fold of control). * statistically significant compared to unstimulated control (p < 0.05, one sample t test)

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