Table 2 Prognostic factors of disease-specific survival. Multivariate analyses with variables of clinical stage, presence or absence of surgery, and histological type were performed. Conducting surgery and cribriform and/or tubular type of histology were independent prognostic factors, reducing 81 and 68% of risk of disease specific death, respectively, while early clinical stage was not independent prognostic factor. Log-rank test for univariate analysis and Cox proportional hazard model for multivariate analysis were adopted