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Table 1 Characterization of the selected antibodies and their expression in granular cell tumors from various sites

From: Granular cell tumors of the tongue: fibroma or schwannoma

Marker

Dilution

Supplier

Character

S-100 protein (rabbit polyclonal antibody)

1:300

DakoCytomation

E-F hand family (granule cells, glia cells, Schwann cells)

Vimentin (mouse monoclonal antibody)

1:300

DakoCytomation

Intermediary filament (granule cells)

PGP 9.5 (mouse monoclonal antibody)

1:300

DakoCytomation

Nerve cells (cell body, axon, granule cells)

NSE (mouse monoclonal antibody)

1:1000

DakoCytomation

Nerve cells (axis-cylinder process)

Calretinin (rabbit polyclonal antibody)

1:10

Spring Biosciences

E-F hand family (Schwann cells, central nerve neurons, mast cells)

GFAP (mouse monoclonal antibody)

1:1000

Novocastra Laboratories

Glia fiber-related acid protein, Schwann cells

CD68 (mouse monoclonal antibody))

1:300

Thermo Fisher Scientific

Highly glycosylated membrane proteins, glycoproteins

Ki-67 (mouse monoclonal antibody)

1:400

DakoCytomation

Proliferation marker

  1. Abbreviations: NSE neuron-specific enolase, GFAP glial fibrillary acidic protein, PGP protein gene product