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Novel use of cranial epidural space in rabbits as an animal model to investigate bone volume augmentation potential of different bone graft substitutes

  • Ivan Valdivia-Gandur1, 2,
  • Wilfried Engelke3,
  • Víctor Beltrán3, 4, 6Email author,
  • Eduardo Borie4,
  • Ramón Fuentes4 and
  • María Cristina Manzanares-Céspedes5
Head & Face Medicine201612:35

Received: 4 July 2016

Accepted: 22 November 2016

Published: 1 December 2016

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting

Original Submission
4 Jul 2016 Submitted Original manuscript
Author responded Author comments
Reviewed Reviewer Report
Resubmission - Version 2
Submitted Manuscript version 2
Reviewed Reviewer Report
Resubmission - Version 3
Submitted Manuscript version 3
22 Nov 2016 Editorially accepted
1 Dec 2016 Article published 10.1186/s13005-016-0131-z

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

Biomedical Department, Universidad de Antofagasta
Odontology Department, Universidad de Antofagasta
Department of Oral and Maxillofacial Surgery, Georg-August-Universität
Faculty of Dentistry, Universidad de La Frontera
Muscular and Skeletal Pathology Research, Human Anatomy and Embryology Unit, Universitat de Barcelona
Clinical Investigation and Dental Innovation Center (CIDIC), Dental School, Universidad de La Frontera