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Table 4 Comparison with existing knowledge

From: Oral lichen planus clinical characteristics in Italian patients: a retrospective analysis

Study

Country

Patients number

F:M

Mean Age

The 3 most affected oral sites

Associated diseases

Most frequent OLP clinical form

Rate of malignant transformation

Salem G. (1989) [28]

Saudi Arabia

4277

n.r.

49

buccal mucosa, gingiva, tongue

no association

atrophic- erosive

0.02 %

Bagan-Sebastian J.V. (1992) [29]

Spain

205

4:1

52.6

buccal mucosa, gingiva, tongue

diabetes

atrophic- erosive

n.r.

Gorsky M. et al. (1996) [30]

Israel

157

1.5:1

52.5

buccal mucosa, gingiva, tongue

no association

reticular

1.3 %

Rossi L. et al. (2000) [31]

Italy

100

1.32:1

58.6

buccal mucosa, gingiva, tongue

C & B hepatitis, diabetes

atrophic- erosive

n.r.

Eisen D. et al. (2002) [32]

USA

723

3:1

52

buccal mucosa, gingiva, tongue

C hepatitis

reticular

0.8 %

Torrente-Castell et al. (2010) [33]

Spain

65

1.56:1

59

buccal mucosa, gingiva, tongue

no association

hyperkeratotic

3.1 %

Xue J.L. (2005) [34]

China

674

1.93:1

50.4

buccal mucosa, lip, tongue

no association

reticular

0.6 %

Ingafou M. (2006) [35]

England

690

1.75:1

52

buccal mucosa, gingiva, tongue

no association

reticular

1.9 %

Pakfetrat A. (2009) [36]

Iran

420

1.85:1

41.6

buccal mucosa, gingiva, tongue

no association

reticular

0.7 %

Bermejo-Fenoll A. (2010) [37]

Spain

550

3.29:1

56.4

buccal mucosa, gingiva, tongue

hypertension, rheumatic diseases gastrointestinal disorders, anxiety & depression

reticular and papular

0.9 %

Shen Z.Y. (2012) [38]

China

518

2.13:1

46.3

buccal mucosa, gingiva, tongue

no association

reticular

1 %

Gümrü B. (2013) [39]

Turkey

370

2.36:1

49.8

buccal mucosa, gingiva, tongue

hypertension, diabetes, anxiety & depression

atrophic- erosive

0.3 %

Present study

Italy

87

1.8:1

58.8

buccal mucosa, gingiva, tongue

hypertension, Diabetes, thyroiditis, C hepatitis

hyperkeratotic

1.15 %

  1. n.r not reported