Skip to main content
Fig. 4 | Head & Face Medicine

Fig. 4

From: First-in-human study and clinical case reports of the alveolar bone regeneration with the secretome from human mesenchymal stem cells

Fig. 4

Clinical, radiographic, and histological observations in Case 2. a The extraction socket remains at the distal part of the right mandibular first premolar. b The socket was filled with MSC-CM/ACS. c The implant placement 8 months after MSC/ACS implantation. The socket is completely regenerated with newly formed bone. A bone biopsy was done where the implant was placed. d-f CT images before and after the SP procedure. d Before the SP procedure. e Three months after the SP procedure. f Six months after the SP procedure. g, h Histologic findings of the specimen from the augmented area (H-E stain) (G; ×12.5 and H; ×40). Newly formed and mature bone was seen throughout the specimen. No inflammatory cells were seen in this specimen. (NB: Newly formed bone)

Back to article page

Head & Face Medicine

ISSN: 1746-160X

Contact us