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Fig. 3 | Head & Face Medicine

Fig. 3

From: First-in-human study and clinical case reports of the alveolar bone regeneration with the secretome from human mesenchymal stem cells

Fig. 3

Histological observation in the reference case. CT images and histology of an SFE case with β-TCP alone are shown. a, b CT images after the SFE procedure. a Three months after the SFE procedure. b Six months after the SFE procedure. c Outline of the specimen. Newly formed bone is scarce, and β-TCP remains much from nasal part to the middle area of the specimen (H-E, ×12.5). d Nasal side of the specimen (×100). e Oral side of the specimen (×100). Replacement of new bone is insufficient. The arrow indicates infiltration of inflammatory cells. Arrow indicates the arrangement of osteoblasts along with the newly formed bone. The dotted arrow indicates that osteoclasts, but the number of osteoclasts was less. Infiltration of the inflammatory cells was seen in the oral part of the specimen. (TCP: β-TCP, NB: Newly formed bone, AB: Alveolar bone)

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