Table 4 Expression factors of angiogenesis-related genes and IRS score related to G and N in OSCC samples
From: Analysis of angiogenic markers in oral squamous cell carcinoma-gene and protein expression
Gene/Protein | G1 (n = 2) | G2 (n = 67) | G3 (n = 14) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
all | IRS score (n = 2) | N- (n = 1) | N+ (n = 1) | all | IRS score (n = 9) | N- (n = 44) | N+ (n = 23) | all | IRS score (n = 3) | N- (n = 8) | N+ (n = 6) | |
VEGF (NM_001025366) | 4.99 ± 3.90 (2) | 8 | 1.09 | 8.9 | 4.22 ± 2.46 (65) | 5.8 | 4.64 ± 2.65 (43) | 3.47 ± 1.81 (23) | 5.62 ± 3.92 (14) | 6 | 3.1 ± 1.25 (8) | 8.29 ± 6.44 (6) |
PECAM1 (NM_000442) | 0.98 ± 0.11 (2) | 0 | 0.87 | 1.09 | 0.57 ± 0.18 (54) | 0 | 0.55 ± 0.18 (36) | 0.59 ± 0.16 (18) | 0.36 ± 0.15 (12) | 0 | 0.24 ± 0.09 (5) | 0.47 ± 0.09 (6) |
EFNB2 (NM_004093) | 1.08 ± 0.69 (2) | 4 | 0.41 | 1.76 | 2.36 ± 0.66 (55) | 6.7 | 2.17 ± 0.92 (38) | 2.72 ± 1.66 (19) | 2.69 ± 1.08 (12) | 1.3 | 2.13 ± 0.9 (5) | 3.16 ± 1.18 (6) |
ANGPT1 (NM_001146) | 1.13 ± 0.17 (2) | 6 | 1.3 | 0.96 | 0.34 ± 0.19 (64) | 0.7 | 0.33 ± 0.19 (41) | 0.36 ± 0.19 (23) | 0.28 ± 0.17 (14) | 0 | 0.36 ± 0.25 (8) | 0.2 ± 0.07 (6) |
ANGPT2 (NM_001147) | 2.55 ± 1.68 (2) | 4.5 | 0.87 | 4.23 | 3.53 ± 1.65 (64) | 5.9 | 3.86 ± 1.89 (41) | 2.94 ± 1.20 (23) | 3.39 ± 1.82 (13) | 6.7 | 1.81 ± 0.45 (6) | 5.25 ± 1.47 (6) |