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Table 4 Expression factors of angiogenesis-related genes and IRS score related to G and N in OSCC samples

From: Analysis of angiogenic markers in oral squamous cell carcinoma-gene and protein expression

Gene/Protein G1 (n = 2) G2 (n = 67) G3 (n = 14)
  all IRS score (n = 2) N- (n = 1) N+ (n = 1) all IRS score (n = 9) N- (n = 44) N+ (n = 23) all IRS score (n = 3) N- (n = 8) N+ (n = 6)
VEGF (NM_001025366) 4.99 ± 3.90 (2) 8 1.09 8.9 4.22 ± 2.46 (65) 5.8 4.64 ± 2.65 (43) 3.47 ± 1.81 (23) 5.62 ± 3.92 (14) 6 3.1 ± 1.25 (8) 8.29 ± 6.44 (6)
PECAM1 (NM_000442) 0.98 ± 0.11 (2) 0 0.87 1.09 0.57 ± 0.18 (54) 0 0.55 ± 0.18 (36) 0.59 ± 0.16 (18) 0.36 ± 0.15 (12) 0 0.24 ± 0.09 (5) 0.47 ± 0.09 (6)
EFNB2 (NM_004093) 1.08 ± 0.69 (2) 4 0.41 1.76 2.36 ± 0.66 (55) 6.7 2.17 ± 0.92 (38) 2.72 ± 1.66 (19) 2.69 ± 1.08 (12) 1.3 2.13 ± 0.9 (5) 3.16 ± 1.18 (6)
ANGPT1 (NM_001146) 1.13 ± 0.17 (2) 6 1.3 0.96 0.34 ± 0.19 (64) 0.7 0.33 ± 0.19 (41) 0.36 ± 0.19 (23) 0.28 ± 0.17 (14) 0 0.36 ± 0.25 (8) 0.2 ± 0.07 (6)
ANGPT2 (NM_001147) 2.55 ± 1.68 (2) 4.5 0.87 4.23 3.53 ± 1.65 (64) 5.9 3.86 ± 1.89 (41) 2.94 ± 1.20 (23) 3.39 ± 1.82 (13) 6.7 1.81 ± 0.45 (6) 5.25 ± 1.47 (6)
  1. Expression factors were experimentally determined in relation to a healthy oral mucosa pool with an expression factor of 1; displayed is the median; ± means Standard deviation; number of tumour samples in groups are in brackets