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Table 3 Expression factors of angiogenesis-related genes and IRS score related to UICC in OSCC samples

From: Analysis of angiogenic markers in oral squamous cell carcinoma-gene and protein expression

Gene/Protein UICC I (n = 15) UICC II (n = 22) UICC III (n = 9) UICC IV (n = 37)
  all IRS score (n = 4) all IRS score (n = 5) all IRS score (n = 2) all IRS score (n = 3)
VEGF (NM_001025366) 3.21 ± 1.70 (14) 5.0 4.73 ± 2.59 (22) 6.4 2.89 ± 1.2 (8) 6.0 5.21 ± 3.3 (37) 7.3
PECAM1 (NM_000442) 0.63 ± 0.18 (9) 0.0 0.48 ± 0.17 (18) 0.0 0.48 ± 0.19 (7) 0.0 0.54 ± 0.17 (31) 0.0
EFNB2 (NM_004093) 1.48 ± 0.48 (11) 0.5 2.22 ± 0.93 (22) 6.0 1.60 ± 0.36 (7) 4.0 2.89 ± 1.48 (31) 7.3
ANGPT1 (NM_001146) 0.47 ± 0.18 (12) 1.5 0.31 ± 0.19 (22) 1.2 0.33 ± 0.25 (9) 0.0 0.33 ± 0.17 (36) 2.0
ANGPT2 (NM_001147) 3.81 ± 2.42 (13) 6.5 3.28 ± 1.46 (21) 4.0 2.96 ± 1.12 (9) 6.0 3.77 ± 1.69 (36) 5.7
  1. Expression factors were experimentally determined in relation to a healthy oral mucosa pool with an expression factor of 1; displayed is the median; ± means Standard deviation; number of tumour samples in groups are in brackets