Table 3 Expression factors of angiogenesis-related genes and IRS score related to UICC in OSCC samples
From: Analysis of angiogenic markers in oral squamous cell carcinoma-gene and protein expression
Gene/Protein | UICC I (n = 15) | UICC II (n = 22) | UICC III (n = 9) | UICC IV (n = 37) | ||||
|---|---|---|---|---|---|---|---|---|
all | IRS score (n = 4) | all | IRS score (n = 5) | all | IRS score (n = 2) | all | IRS score (n = 3) | |
VEGF (NM_001025366) | 3.21 ± 1.70 (14) | 5.0 | 4.73 ± 2.59 (22) | 6.4 | 2.89 ± 1.2 (8) | 6.0 | 5.21 ± 3.3 (37) | 7.3 |
PECAM1 (NM_000442) | 0.63 ± 0.18 (9) | 0.0 | 0.48 ± 0.17 (18) | 0.0 | 0.48 ± 0.19 (7) | 0.0 | 0.54 ± 0.17 (31) | 0.0 |
EFNB2 (NM_004093) | 1.48 ± 0.48 (11) | 0.5 | 2.22 ± 0.93 (22) | 6.0 | 1.60 ± 0.36 (7) | 4.0 | 2.89 ± 1.48 (31) | 7.3 |
ANGPT1 (NM_001146) | 0.47 ± 0.18 (12) | 1.5 | 0.31 ± 0.19 (22) | 1.2 | 0.33 ± 0.25 (9) | 0.0 | 0.33 ± 0.17 (36) | 2.0 |
ANGPT2 (NM_001147) | 3.81 ± 2.42 (13) | 6.5 | 3.28 ± 1.46 (21) | 4.0 | 2.96 ± 1.12 (9) | 6.0 | 3.77 ± 1.69 (36) | 5.7 |