Skip to main content

Table 2 Expression factors of angiogenesis-related genes and IRS score related to T and N in OSCC samples

From: Analysis of angiogenic markers in oral squamous cell carcinoma-gene and protein expression

Gene/Protein

T1 + T2

T3 + T4

 

all (n = 56)

IRS score (n = 10)

N- (n = 39)

N+ (n = 17)

all (n = 27)

IRS score (n = 4)

N- (n = 14)

N+ (n = 13)

VEGF (NM_001025366)

4.13 ± 2.70 (53)

5.8

4.10 ± 2.40 (37)

4.91 ± 4.15 (16)

4.81 ± 2.32 (27)

7.0

5.32 ± 2.68 (14)

4.25 ± 1.72 (13)

PECAM1 (NM_000442)

0.76 ± 0.40 (41)

0

0.55 ± 0.20 (28)

0.58 ± 0.16 (13)

0.52 ± 0.18 (24)

0

0.49 ± 0.21 (13)

0.54 ± 0.14 (11)

EFNB2 (NM_004093)

2.24 ± 1.08 (46)

4.0

2.06 ± 0.90 (32)

2.56 ± 1.25 (14)

2.39 ± 1.12 (24)

5.5

2.4 0 ± 1.04 (13)

2.39 ± 1.22 (11)

ANGPT1 (NM_001146)

0.51 ± 0.32 (51)

1.2

0.41 ± 0.32 (35)

0.33 ± 0.20 (16)

0.29 ± 0.16 (27)

1.5

0.27 ± 0.15 (14)

0.33 ± 0.18 (13)

ANGPT2 (NM_001147)

3.43 ± 1.73 (52)

5.2

3.52 ± 1.73 (35)

3.51 ± 1.08 (17)

3.91 ± 1.92 (25)

5.8

4.40 ± 1.81 (13)

3.39 ± 1.99 (12)

  1. Expression factors were experimentally determined in relation to a healthy oral mucosa pool with an expression factor of 1; displayed is the median; ± means Standard deviation; number of tumour samples in groups are in brackets