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Table 1 Comparison between ALHE and Kimura's disease.

From: Angiolymphoid hyperplasia with eosinophilia: efficacy of isotretinoin?

  ALHE Kimura's disease
Presentation Superficial papules or nodules
Multiple lesions
Large subcutaneous nodules
Usually one lesion
Localisation Head and neck Head and neck
Population Third and fourth decades
Caucasian
Female
Younger age
Asian
Male
Regional lymph nodes No Possible
Skeletal involvement No Possible
Blood eosinophilia Mild Marked
Elevated serum IgE Infrequent Frequent
Histology Marked lymphocytic infiltrate and increased mast cell numbers
Exuberant angiomatoid proliferation, masses of uncanalized epithelioid or histiocytoid endothelial cells
Well developed lymphoid follicles
Capillary proliferation with large thick-walled vessels
Origin of the disease Vascular origin (endothelial cell) Chronic inflammatory process