From: Smoothened gene alterations in keratocystic odontogenic tumors
Variation | Protein sequence change | PROVEAN prediction | Sift prediction | |||||
---|---|---|---|---|---|---|---|---|
Row_No. | Protein_ID | Position | Residue_REF | Residue_ALT | Score | Prediction (cutoff = -2.5) | Score | Prediction (cutoff = 0.05) |
1 | NP_005622.1 | 166 | F | I | -5.385 | Deleterious | 0.002 | Damaging |
2 | NP_005622.1 | 334 | V | G | -5.063 | Deleterious | 0.003 | Damaging |
3 | NP_005622.1 | 590 | S | T | -1.487 | Neutral | 0.219 | Tolerated |