Table 1 Results of cell count
From: In vitro inhibition of HUVECs by low dose methotrexate – insights into oral adverse events
Cell number per unit | Control | 1 nM | MTX-concentration | |||
|---|---|---|---|---|---|---|
10 nM | 10 nM | 10 nM | ||||
Day 1 | mean | 13.50 | 17.83 | 28.67 | 25.50 | 33.17 |
SD | 4.76 | 5.74 | 13.55 | 9.01 | 7.49 | |
95% CI | 10.48-16.52 | 11.81-23.86 | 14.45-42.88 | 16.05-34.95 | 25.30-41.03 | |
Day 3 | mean | 37.58 | 54.02 | 74.01 | 65.83 | 85.17 |
SD | 15.72 | 19.22 | 18.24 | 9.04 | 12.07 | |
95% CI | 27.59-47.57 | 33.84-74.16 | 54.86-93.14 | 56.34-75.32 | 72.50-97.84 | |
Day 6 | mean | 159.92 | 110.67 | 69.33 | 63.67 | 70.50 |
SD | 47.86 | 15.85 | 19.63 | 7.23 | 10.21 | |
95% CI | 129.51-190.33 | 94.04-127.30 | 48.73-89.94 | 56.08-71.25 | 59.78-81.22 | |
Day 8 | mean | 222.04 | 97.51 | 59.83 | 56.17 | 63.67 |
SD | 40.72 | 18.08 | 23.09 | 12.70 | 12.31 | |
95% CI | 192.13-247.87 | 78.53-116.47 | 35.60-84.07 | 42.84-69.50 | 50.75-76.58 | |
Day 10 | mean | 221.17 | 68.00 | 31.17 | 33.53 | 36.33 |
SD | 51.30 | 30.68 | 7.71 | 16.79 | 6.22 | |
95% CI | 188.57-253.76 | 35.80-100.20 | 23.08-39.25 | 15.88-51.12 | 29.81-42.86 | |
Day 14 | mean | 210.92 | 90.83 | 41.17 | 37.83 | 40.83 |
SD | 55.25 | 49.06 | 8.09 | 16.52 | 11.48 | |
95% CI | 175.82-246.02 | 39.34-142.34 | 32.68-49.65 | 20.49-55.17 | 28.79-52.88 | |